Autism and Mitochondria Research
Return to Index | All research on one page
Chugani DC, Sundram BS, Behen M, Lee ML, Moore GJ. Evidence of altered energy metabolism in autistic children. Prog Neuropsychopharmacol Biol Psychiatry. 1999 May;23(4):635-41.
Clark-Taylor T, Clark-Taylor BE. Is autism a disorder of fatty acid metabolism? Possible dysfunction of mitochondrial beta-oxidation by long chain acyl-CoA dehydrogenase. Med Hypotheses 62(6): 970-5.
Ehrhart J, Zeevalk GD. Cooperative interaction between ascorbate and glutathione during mitochondrial impairment in mesencephalic cultures. J Neurochem 2003 86(6):1487-97.
Fernandez-Checa JC et al. Oxidative stress: role of mitochondria and protection by glutathione. Biofactors. 1998;8(1-2):7-11.
Filipek PA, Juranek J, et al. Relative carnitine deficiency in autism. J Autism Dev Disord 34(6): 615-23, 2004, 2004.
Filipek PA, Juranek J, et al. Mitochondrial dysfunction in autistic patients with 15q inverted duplication. Ann Neurol 53(6): 801-4, 2003.
Fillano JJ, Goldenthal MJ, et al. Mitochondrial dysfunction in patients with hypotonia, epilepsy, autism, and developmental delay: HEADD syndrome. J Child Neurol 17(6): 435-9., 2002.
Gargus JJ, Imtiaz F. Mitochondrial energy-deficient endophenotype in autism. Am J Biochem Biotechnol 4(2): 198-207, 2008.
Graf WD, Marin-Garcia J, et al. Autism associated with the mitochondrial DNA G8363A transfer RNA(Lys) mutation. J Child Neurol 15(6): 357-61, 2000.
Holtzman D. Autistic spectrum disorders and mitochondrial encephalopathies. Acta Paediatr. 2008 Jul;97(7):859-60.
Kidd PM. Neurodegeneration from mitochondrial insufficiency: nutrients, stem cells, growth factors, and prospects for brain rebuilding using integrative management. Altern Med Rev. 2005 Dec;10(4):268-93.
Lerman-Sagie T, et al. Should autistic children be evaluated for mitochondrial disorders. J Child Neurol 19(5): 379-81, 2004.
Lombard, J. Autism: a mitochondrial disorder? Med Hypotheses 50(6): 497-500, 1998.
Oliveira G, Ataide A, et al. Epidemiology of autism spectrum disorder in Portugal: prevalence, clinical characterization, and medical conditions. Dev Med Child Neurol 49(10): 726-33, 2007.
Oliveira G, Diogo L, et al. Mitochondrial dysfunction in autism spectrum disorders: a population-based study. Dev Med Child Neurol 47(3): 185-9, 2005.
Poling JS, et al. Developmental regression and mitochondrial dysfunction in a child with autism. J Child Neurol 21(2): 170-2, 2006.
Pons R, Andreu AL, et al. Mitochondrial DNA abnormalities and autistic spectrum disorders. J Pediatr 144(1): 81-5, 2004.
Ramoz N, Reichert JG, et al. Linkage and association of the mitochondrial aspartate/glutamate carrier SLC25A12 gene with autism. Am J Psychiatry 161(4): 662-9, 2004.
Rossignol DA, Bradstreet JJ. Evidence of mitochondrial dysfunction in autism and implications for treatment. A J Biochem Biotechnol 4(2): 208-217, 2008.
Segurado R, Conroy J, et al. Confirmation of association between autism and the mitochondrial aspartate/glutamate carrier SLC25A12 gene on chromosome 2q31. Am J Psychiatry 162(11): 2182-4, 2005.
Silverman JM, Buxbaum JD, et al. Autism-related routines and rituals associated with a mitochondrial aspartate/glutamate carrier SLC25A12 polymorphism. Am J Med Genet B Neuropsychiatr Genet, 2007.
Smith M, Spence MA, Flodman P. Nuclear and mitochondrial genome defects in autisms. Ann. N.Y. Acad. Sci. 1151:102–132, 2009.
Trushina E, McMurray CT. Oxidative stress and mitochondrial dysfunction in neurodegenerative diseases. Neuroscience 145(4): 1233-48, 2007.
Tsao CY, Mendell JR. Autistic disorder in 2 children with mitochondrial disorders. J Child Neurol 2007: 22(9): 1121-3.
Weissman JR, et al. Mitochondrial disease in autism spectrum disorder patients: a cohort analysis. PLoS ONE. 2008;3(11):e3815.