Autism and Oxidative Stress Research
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Abbott LC, Nahm SS. Neuronal nitric oxide synthase expression in cerebellar mutant mice. Cerebellum 2004: 3(3): 141-51.
Anderson MP, Hooker BS, et al. Bridging from cells to cognition in autism pathophysiology: biological pathways to defective brain function and plasticity. A J Biochem Biotechnol 2008: 4(2): 167-176.
Bell JG, MacKinlay EE, et al. Essential fatty acids and phospholipase A2 in autistic spectrum disorders. Prostaglandins Leukot Essent Fatty Acids 2004: 71(4): 201-4.
Bell JG, Sargent JR, et al. Red blood cell fatty acid compositions in a patient with autistic spectrum disorder: a characteristic abnormality in neurodevelopmental disorders? Prostaglandins Leukot Essent Fatty Acids 2000: 63(1-2): 21-5.
Blaylock, R. Interactions of cytokines, excitotoxins, and reactive nitrogen and oxygen species in autism spectrum disorders. J Amer Nutr Assoc 2003: 6: 21-35.
Boso M, Emanuele E, et al. Alterations of circulating endogenous secretory RAGE and S100A9 levels indicating dysfunction of the AGE-RAGE axis in autism. Neurosci Lett 2006: 410(3): 169-73.
Chauhan A, Chauhan V. Oxidative stress in autism. Pathophysiology 2006: 13(3): 171-81.
Chauhan A, Chauhan V, et al. Oxidative stress in autism: increased lipid peroxidation and reduced serum levels of ceruloplasmin and transferrin--the antioxidant proteins. Life Sci 2004: 75(21): 2539-49.
Chauhan A, Sheikh A, et al. Increased copper-mediated oxidation of membrane phosphatidylethanolamine in autism. Am J Biochem Biotechnol 2008:4(2): 95-100.
Chauhan V, Chauhan A, et al. Alteration in amino-glycerophospholipids levels in the plasma of children with autism: a potential biochemical diagnostic marker. Life Sci 2004: 74(13): 1635-43.
Chez MG, Buchanan CP, et al. Double-blind, placebo-controlled study of L-carnosine supplementation in children with autistic spectrum disorders. J Child Neurol 2002: 17(11): 833-7.
Danfors T, von Knorring AL, et al. Tetrahydrobiopterin in the treatment of children with autistic disorder: a double-blind placebo-controlled crossover study. J Clin Psychopharmacol 2005: 25(5): 485-9.
Deth R, et al. How environmental and genetic factors combine to cause autism: A redox/methylation hypothesis. Neurotoxicology 2008: 29(1): 190-201.
Evans TA, Siedlak SL, et al. The autistic phenotype exhibits a remarkably localized modification of brain protein by products of free radical-induced lipid oxidation. Am J Biochem Biotechnol 2008: 4(2): 61-72.
Flora SJ, Pande M, Kannan GM, Mehta A. Lead induced oxidative stress and its recovery following co-administration of melatonin or N-acetylcysteine during chelation with succimer in male rats. Cell Mol Biol (Noisy-le-grand). 2004;50.
Jackson MJ, Garrod PJ. Plasma zinc, copper, and amino acid levels in the blood of autistic children. J Autism Child Schizophr 1978: 8(2): 203-8.
James SJ, Cutler P, Melnyk S, Jernigan S, Janak L, Gaylor DW, Neubrander JA. Metabolic biomarkers of increased oxidative stress and impaired methylation capacity in children with autism. Am J Clin Nutr. 2004 Dec;80(6):1611-7.
James SJ, et al. Metabolic endophenotype and related genotypes are associated with oxidative stress in children with autism. Am J Med Genet B Neuropsychiatr Genet. 2006 Aug 17.
James SJ, Slikker W 3rd, Melnyk S, New E, Pogribna M, Jernigan S. Thimerosal neurotoxicity is associated with glutathione depletion: protection with glutathione precursors. Neurotoxicology. 2005 Jan;26(1):1-8.
James SJ, et al. Efficacy of methylcobalamin and folinic acid treatment on glutathione redox status in children with autism. Am J Clin Nutr. 2008 Dec 3.
Johannesson T, Kristinsson J, et al. [Neurodegenerative diseases, antioxidative enzymes and copper. A review of experimental research.]. Laeknabladid 2003: 89(9): 659-671.
Johnson, S. Micronutrient accumulation and depletion in schizophrenia, epilepsy, autism and Parkinson's disease? Med Hypotheses 2001: 56(5): 641-5.
Jory J, McGinnis WR. Red-cell trace minerals in children with autism. Am J Biochem Biotechnol 2008: 4(2): 101-104.
Junaid MA, Kowal D, et al. Proteomic studies identified a single nucleotide polymorphism in glyoxalase I as autism susceptibility factor. Am J Med Genet A 2004: 131(1): 11-7.
Kazutoshi N, Naoko N, Emiko T, Man U, Miyuki T, Kaori S. A Preliminary Study of Methylcobalamin Therapy in Autism. J Tokyo Women's Medical University. 2005; 75(3/4);64-69.
Keithahn C, Lerchl A. 5-hydroxytryptophan is a more potent in vitro hydroxyl radical scavenger than melatonin or vitamin C. J Pineal Res. 2005 Jan;38(1):62-6.
MacFabe, DF, Rodríguez-Capote K, et al. A novel rodent model of autism: intraventricular infusions of propionic acid increase locomotor activity and induce neuroinflammation and oxidative stress in discrete regions of adult rat brain. Am J Biochem Biotechnol 2008: 4(2): 146-166.
Mahadik SP, Scheffer RE. Oxidative injury and potential use of antioxidants in schizophrenia. Prostaglandins Leukot Essent Fatty Acids. 1996 Aug;55(1-2):45-54.
McGinnis WR. Oxidative stress in autism. Altern Ther Health Med 2004: 10(6): 22-36; quiz 37, 92.
McGinnis WR. Oxidative stress in autism. Altern Ther Health Med 2005: 11(1): 19.
McGinnis WR. Could oxidative stress from psychosocial stress affect neurodevelopment in autism? J Autism Dev Disord 2007: 37(5): 993-4.
Miller DM, Woods JS. Urinary porphyrins as biological indicators of oxidative stress in the kidney. Interaction of mercury and cephaloridine. Biochem Pharmacol 1993: 46(12): 2235-41.
Ming X, Stein TP, Brimacombe M, Johnson WG, Lambert GH, Wagner GC. Increased excretion of a lipid peroxidation biomarker in autism. Prostaglandins Leukot Essent Fatty Acids. 2005 Nov;73(5):379-84.
Ming X, et al. Evidence of Oxidative Stress in Autism Derived from Animal Models. Am J Biochem Biotechnol 4(2): 218-225, 2008.
Ng F, Berk M, et al. Oxidative stress in psychiatric disorders: evidence base and therapeutic implications. Int J Neuropsychopharmacol 2008: 1-26.
Pasca SP, Nemes B, et al. High levels of homocysteine and low serum paraoxonase 1 arylesterase activity in children with autism. Life Sci 2006: 78(19): 2244-8.
Reiter RJ, Tan DX, Burkhardt S. Reactive oxygen and nitrogen species and cellular and organismal decline: amelioration with melatonin. Mech Ageing Dev. 2002 Apr 30;123(8):1007-19.
Ross M. A. Could oxidative stress be a factor in neurodevelopmental disorders? Prostaglandins Leukot Essent Fatty Acids 2000: 63(1-2): 61-3.
Rossignol DA, Rossignol LW. The effects of hyperbaric oxygen therapy on oxidative stress, inflammation, and symptoms in children with autism: an open-label pilot study. BMC Pediatr 2007: 7(1): 36.
Sajdel-Sulkowska EM, Lipinski B, et al. Oxidative stress in autism: elevated cerebellar 3-nitrotyrosine levels. Am J Biochem Biotechnol 2008: 4(2): 73-84.
Sierra C, Vilaseca MA, et al. Oxidative stress in Rett syndrome. Brain Dev 2001: 23 Suppl 1: S236-9.
Sogut S, Zoroglu SS, et al. Changes in nitric oxide levels and antioxidant enzyme activities may have a role in the pathophysiological mechanisms involved in autism. Clin Chim Acta 2003: 331(1-2): 111-7.
Sokol DK, Chen D, et al. High levels of Alzheimer beta-amyloid precursor protein (APP) in children with severely autistic behavior and aggression. J Child Neurol 2006: 21(6): 444-9.
Suh JH, Walsh WJ, et al. Altered sulfur amino acid metabolism in immune cells of children diagnosed with autism. Am J Biochem Biotechnol 2008: 4(2): 105-113.
Tchantchou F, Graves M, Shea TB. Expression and activity of methionine cycle genes are altered following folate and vitamin E deficiency under oxidative challenge: modulation by apolipoprotein E-deficiency. Nutr Neurosci. 2006 Feb-Apr;9(1-2):17-24.
Torsdottir G, Hreidarsson S, et al. Ceruloplasmin, superoxide dismutase and copper in autistic patients. Basic Clin Pharmacol Toxicol 2005: 96(2): 146-8.
Yao Y, Walsh WJ, et al. Altered vascular phenotype in autism: correlation with oxidative stress. Arch Neurol 2006: 63(8): 1161-4.
Yorbik O, Sayal A, Akay C, Akbiyik DI, Sohmen T. Investigation of antioxidant enzymes in children with autistic disorder. Prostaglandins Leukot Essent Fatty Acids. 2002 Nov;67(5):341-3.
Zoroglu SS, Armutcu F, et al. Increased oxidative stress and altered activities of erythrocyte free radical scavenging enzymes in autism. Eur Arch Psychiatry Clin Neurosci. 2004: 254(3): 143-7.